Article
Induction of string rescues the neuroblast proliferation defect in trol mutant animals.
Genesis (New York, N.Y. : 2000) - 1 Aug 2003
Park Youngji, Ng Cristina, Datta Sumana
Abstract excerpt
In trol mutants, neuroblasts fail to exit G1 for S phase. Increasing string expression in trol mutants rescues the number of S phase neuroblasts without an increase in M phase neuroblasts. Decreasing string expression further decreased the number of S phase neuroblasts. Coexpression of cyclin E and string did not produce additional S phase cells. Unlike cyclin E, cdk2, and cdk2AF, elevated expression of neither...
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