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Article

Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma

2020-11-19

Abstract excerpt

<h4>Background: </h4> Patients with severe asthma may have a greater risk of dying from COVID-19 disease. Angiotensin converting enzyme-2 (ACE2) and the enzyme proteases, transmembrane protease serine 2 (TMPRSS2) and FURIN, are needed for viral attachment and invasion into host cells. Methods. We examined microarray mRNA expression of ACE2, TMPRSS2 and FURIN in sputum, bronchial brushing and bronchial biopsies of...

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Identifiers and source

Literature Corpus work
c1597984-ff2f-5dba-aa60-b736b15aa94b
DOI
10.22541/au.160579638.84277232/v1
Open publication

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Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthmaDOI 10.22541/au.160579638.84277232/v1
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