Article
CYP2C9 and CYP2C19 Allele and Haplotype Distributions in Four Mestizo Populations from Western Mexico: An Interethnic Comparative Study.
Genetic testing and molecular biomarkers - 1 Nov 2016
Saldaña-Cruz Ana Miriam, León-Moreno Lilia Carolina, Sánchez-Corona José, Santiago Daniel Alejandro Márquez-de, Mendoza-Carrera Francisco, Castro-Martínez Xochitl Helga, García-Zapién Alejandra Guadalupe, Morán-Moguel María Cristina, Flores-Martínez Silvia Esperanza
Abstract excerpt
AIMS: Polymorphisms in the CYP2C9 and CYP2C19 genes confer potential risk for specific adverse drug reactions and therapeutic effect failure. Their frequencies differ among ethnic groups. This study was aimed to describe the distribution of CYP2C9 and CYP2C19 alleles and haplotypes in four Mestizo populations from Western Mexico and their comparison with the reported data from other ethnic groups. METHODS: The...
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