Article
Genetic polymorphism of CYP2C9 and CYP2C19 in a Bolivian population: an investigative and comparative study.
European journal of clinical pharmacology - 1 May 2005
Bravo-Villalta Heydy V, Yamamoto Koujirou, Nakamura Katsunori, Bayá Ana, Okada Yuko, Horiuchi Ryuya
Abstract excerpt
OBJECTIVE: Several reports of CYP2C genetic polymorphism demonstrate its potential clinical role in determining both inter-individual and inter-ethnic differences in drug efficacy. We estimated the distribution of CYP2C9 and CYP2C19 common variants in the Bolivian population (a South American population), and compared these data with those from Asian, African, Caucasian and Oceanian populations. METHODS: Genomic...
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