Article
Allele frequency distribution of CYP2C9 2 and CYP2C9 3 polymorphisms in six Mexican populations.
Gene - 10 Jul 2013
Castelán-Martínez Osvaldo D, Hoyo-Vadillo Carlos, Sandoval-García Emmanuel, Sandoval-Ramírez Lucila, González-Ibarra Miriam, Solano-Solano Gloria, Gómez-Díaz Rita A, Parra Esteban J, Cruz Miguel, Valladares-Salgado Adán
Abstract excerpt
Allele frequency differences of functional CYP2C9 polymorphisms are responsible for some of the variation in drug response observed in human populations. The most relevant CYP2C9 functional variants are CYP2C9*2 (rs1799853) and CYP2C9 3 (rs1057910). These polymorphisms show variation in allele frequencies among different population groups. The present study aimed to analyze these polymorphisms in 947...
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