Article
Genetic polymorphism of cytochrome P450 2C19 in Mexican Americans: a cross-ethnic comparative study.
Clinical pharmacology and therapeutics - 1 Jul 2006
Luo Huai-Rong, Poland Russell E, Lin Keh-Ming, Wan Yu-Jui Yvonne
Abstract excerpt
OBJECTIVES: Our objectives were to investigate cytochrome P450 (CYP) 2C19 polymorphism in Mexican Americans and compare the findings with those in 4 other ethnic groups. METHODS: The CYP2C19 genotype (n = 346) and S-mephenytoin hydroxylation phenotype (n = 220) were studied in a Mexican American population from Los Angeles County. Another 4 ethnic groups, African Americans (n = 236), whites (n = 273), East Asians...
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