Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards.

The pharmacogenomics journal - 1 Jan 2004

LLerena A, Dorado P, O'Kirwan F, Jepson R, Licinio J, Wong M-L

Abstract excerpt

Interethnic differences in cytochrome P450 polymorphism might be responsible, at least in part, for the variations in drug disposition between ethnic groups. Of the various CYP2C9 alleles, CYP2C9*2 and CYP2C9*3 have been reported to have altered catalytic activities compared to the wild-type CYP2C9*1. The present study is aimed at analysing the CYP2C9 polymorphism in a Mexican-American compared with a Spanish...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Chi-Square Distribution
Share to Confidence Intervals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

Share to Gene Frequency

Share to Mexican Americans

Share to White People

Source

Identifiers

PMID: 15452553
DOI: 10.1038/sj.tpj.6500278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards.PMID 15452553Read ↗

CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards.Semantic proximity Read ↗

Worldwide interethnic variability and geographical distribution of CYP2C9 genotypes and phenotypes.Semantic proximity Read ↗

Allele frequency distribution of CYP2C9 2 and CYP2C9 3 polymorphisms in six Mexican populations.Semantic proximity Read ↗

Prevalence of CYP2C9 polymorphisms in the south of Europe.Semantic proximity Read ↗

Genetic polymorphism of cytochrome P450 2C19 in Mexican Americans: a cross-ethnic comparative study.Semantic proximity Read ↗

Impact of Genetic Polymorphisms in CYP2C9 and CYP2C19 on the Pharmacokinetics of Clinically Used DrugsSemantic proximity Read ↗

Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance.Semantic proximity Read ↗

High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population.Semantic proximity Read ↗

The pharmacogenetics of CYP2C9 and CYP2C19: ethnic variation and clinical significance.Semantic proximity Read ↗

Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals.Semantic proximity Read ↗

Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects.Semantic proximity Read ↗

Losartan hydroxylation phenotype in an Ecuadorian population: influence of CYP2C9 genetic polymorphism, habits and gender.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.