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Article

Distribution of ABCB1, CYP3A5, CYP2C19, and P2RY12 gene polymorphisms in a Mexican Mestizos population.

Molecular biology reports - 1 Oct 2014

Vargas-Alarcón Gilberto, Ramírez-Bello Julián, de la Peña Aurora, Calderón-Cruz Beatriz, Peña-Duque Marco Antonio, Martínez-Ríos Marco Antonio, Ramírez-Fuentes Silvestre, Pérez-Méndez Oscar, Fragoso José Manuel

Abstract excerpt

The aim of the present study was to establish the gene frequency of six polymorphisms of the ABCB1, CYP3A5, CYP2C19, and P2RY12 genes in a population resident of Mexico City. The proteins encoded by these genes have been associated with the absorption, and biotransformation of clopidogrel. The ABCB1 T3435C, CYP3A5 V3 A6986G, P2RY12 G52T, P2RY12 C34T, CYP2C19 V2 and V3 (positions G681A and G636A, respectively),...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Source

Identifiers

PMID: 25106522
DOI: 10.1007/s11033-014-3590-y

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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