Article
Genetically Determined Response to Artemisinin Treatment in Western Kenyan Plasmodium falciparum Parasites.
PloS one - 1 Jan 2016
Chebon Lorna J, Ngalah Bidii S, Ingasia Luicer A, Juma Dennis W, Muiruri Peninah, Cheruiyot Jelagat, Opot Benjamin, Mbuba Emmanuel, Imbuga Mabel, Akala Hoseah M, Bulimo Wallace, Andagalu Ben, Kamau Edwin
Abstract excerpt
Genetically determined artemisinin resistance in Plasmodium falciparum has been described in Southeast Asia. The relevance of recently described Kelch 13-propeller mutations for artemisinin resistance in Sub-Saharan Africa parasites is still unknown. Southeast Asia parasites have low genetic diversity compared to Sub-Saharan Africa, where parasites are highly genetically diverse. This study attempted to elucidate...
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