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Article

Rigid Cooperation of Per1 and Per2 proteins.

Scientific reports - 9 Sept 2016

Tamiya Hiroyuki, Ogawa Sumito, Ouchi Yasuyoshi, Akishita Masahiro

Abstract excerpt

Period circadian clock (Per) genes Per1 and Per2 have essential roles in circadian oscillation. In this study, we identified a new role of Per1-Per2 cooperation, and its mechanism, using our new experimental methods. Under constant light conditions, the period length of Per1 and Per2 knockout mice depended on the copy number ratio of Per1:Per2. We then established a light-emitting diode-based lighting system that...

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Identifiers

PMID: 27609640
DOI: 10.1038/srep32769
PMCID: PMC5016722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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