Article
Photic entrainment of period mutant mice is predicted from their phase response curves.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Sept 2010
Pendergast Julie S, Friday Rio C, Yamazaki Shin
Abstract excerpt
A fundamental property of circadian clocks is that they entrain to environmental cues. The circadian genes, Period1 and Period2, are involved in entrainment of the mammalian circadian system. To investigate the roles of the Period genes in photic entrainment, we constructed phase response curves (PRC) to light pulses for C57BL/6J wild-type, Per1(-/-), Per2(-/-), and Per3(-/-) mice and tested whether the PRCs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
