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Article

Core-clock genes Period 1 and 2 regulate visual cascade and cell cycle components during mouse eye development.

Biochimica et biophysica acta. Gene regulatory mechanisms - 1 Oct 2020

Bagchi Udita, Gegnaw Shumet T, Milićević Nemanja, Sandu Cristina, Ten Brink Jacoline B, Jongejan Aldo, Hicks David, Moerland Perry D, Felder-Schmittbuhl Marie-Paule, Bergen Arthur A

Abstract excerpt

The retinas from Period 1 (Per1) and Period 2 (Per2) double-mutant mice (Per1-/-Per2Brdm1) display abnormal blue-cone distribution associated with a reduction in cone opsin mRNA and protein levels, up to 1 year of age. To reveal the molecular mechanisms by which Per1 and Per2 control retina development, we analyzed genome-wide gene expression differences between wild-type (WT) and Per1-/-Per2Brdm1 mice across...

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Identifiers

PMID: 32795630
DOI: 10.1016/j.bbagrm.2020.194623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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