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Article

Distinct functions of Period2 and Period3 in the mouse circadian system revealed by in vitro analysis.

PloS one - 1 Jan 2010

Pendergast Julie S, Friday Rio C, Yamazaki Shin

Abstract excerpt

The mammalian circadian system, which is composed of a master pacemaker in the suprachiasmatic nuclei (SCN) as well as other oscillators in the brain and peripheral tissues, controls daily rhythms of behavior and physiology. Lesions of the SCN abolish circadian rhythms of locomotor activity and transplants of fetal SCN tissue restore rhythmic behavior with the periodicity of the donor's genotype, suggesting that...

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Identifiers

PMID: 20072700
DOI: 10.1371/journal.pone.0008552
PMCID: PMC2804141

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Source receipt: pubmed, retrieved 7 Sept 2026.

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