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Article

A genetic variant study of bortezomib-induced peripheral neuropathy in Chinese multiple myeloma patients.

Oncology research - 1 Jan 2024

Zhang Yan, Zhang Heyang, Wang Jing, Wei Xin, Qu Y I, Xu Feng, Zhang Lijun

Abstract excerpt

Background: Bortezomib results in peripheral neuropathy (PN) in approximately 50% of patients, during multiple myeloma (MM) treatment, a complication known as Bortezomib-induced peripheral neuropathy (BIPN). The drug response varies among individuals. Genetic factor may play an important role in BIPN. Methods: A next-generation sequencing (NGS) panel containing 1659 targets from 233 genes was used to identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38686049
DOI: 10.32604/or.2023.043922
PMCID: PMC11055991

Genes

MTHFR
ALDH1A1
CYP2A6
EPHX1
HTR7
MME

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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