Article
FAS-670A/G single nucleotide polymorphism may be associated with human T lymphotropic virus-1 infection and clinical evolution to TSP/HAM.
Virus research - 1 Jan 2012
Vallinoto Antonio Carlos R, Santana Bárbara B, dos Santos Ethienne L, Santo Rafaela R do Espírito, Hermes Renata B, Sousa Rita Catarina M, Cayres-Vallinoto Izaura, Machado Luiz Fernando A, Ishak Marluísa O G, Ishak Ricardo
Abstract excerpt
FAS and FASLG genes are closely linked to the apoptosis mechanism of the immune system and several polymorphisms in these genes have been associated with susceptibility to diseases. The present study investigated the polymorphisms at positions -670 in the FAS gene, and -169 and -124 in the FASLG gene, among HTLV-1 infected subjects. Blood samples from HTLV infected subjects and seronegative individuals were...
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