Article
IL6 and FAS/FASL gene polymorphisms may be associated with disease progression in HIV-1-positive ethnically mixed patients.
Journal of medical virology - 1 Aug 2020
Loureiro Dos Reis Marília M, Queiroz Maria A F, da Silva Bosco C M, da Silva Duarte Alberto J, Casseb Jorge, Arganaraz Gustavo A, Vallinoto Antonio C R, Argañaraz Enrique R
Abstract excerpt
The progression of AIDS depends on the complex host and virus interactions. The most important disease progression hallmarks are immune activation and apoptosis. In this study, we address the prevalence of polymorphisms related to proinflammatory and apoptotic genes, such as IFNG (+874T/A), TNF (308G/A), IL6 (-174G/C), IL8 (-251A/T), FAS (-670A/G), and FASL (-124A/G) in 160 ethnically mixed HIV-1-infected...
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