Article
Novel HLA-DP region susceptibility loci associated with severe acute GvHD.
Bone marrow transplantation - 1 Jan 2017
Goyal R K, Lee S J, Wang T, Trucco M, Haagenson M, Spellman S R, Verneris M, Ferrell R E
Abstract excerpt
Despite HLA allele matching, significant acute GvHD remains a major barrier to successful unrelated donor BMT. We conducted a genome-wide association study (GWAS) to identify recipient and donor genes associated with the risk of acute GvHD. A case-control design (grade III-IV versus no acute GvHD) and pooled GWA approach was used to study European-American recipients with hematological malignancies who received...
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