Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation.

doi:10.1182/blood-2017-08-801449

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation.

Blood - 15 Feb 2018

Morishima Satoko, Shiina Takashi, Suzuki Shingo, Ogawa Seishi, Sato-Otsubo Aiko, Kashiwase Koichi, Azuma Fumihiro, Yabe Toshio, Satake Masahiro, Kato Shunichi, Kodera Yoshihisa, Sasazuki Takehiko, Morishima Yasuo

Abstract excerpt

HLA-DPB1 T-cell epitope (TCE) mismatching algorithm and rs9277534 SNP at the 3' untranslated region (3'UTR) in the HLA-DPB1 gene are key factors for transplant-related events in unrelated hematopoietic cell transplantation (UR-HCT). However, the association of these 2 mechanisms has not been elucidated. We analyzed 19 frequent HLA-DPB1 alleles derived from Japanese healthy subjects by next-generation sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Graft vs Host Disease

Share to Hematopoietic Stem Cell Transplantation

Share to Histocompatibility Testing

Share to HLA-DP beta-Chains

Share to Infant, Newborn

Share to Unrelated Donors

Source

Open in PubMed Open full text

Identifiers

PMID: 29246901
DOI: 10.1182/blood-2017-08-801449
PMCID: PMC5824334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation.PMID 29246901Read ↗

HLA-DPB1 and DPA1 ~ DPB1 linkage mismatch affects the survival of recipients receiving HLA-14/14 matched unrelated donor HSCT.Semantic proximity Read ↗

The biological significance of HLA‐DP gene variation in haematopoietic cell transplantationSemantic proximity Read ↗

Machine Learning Insights into HLA Noncoding Sequence Mismatches and Their Impact on DPB1 Matching in Hematopoietic Cell TransplantationSemantic proximity Read ↗

High HLA-DP Expression and Graft-versus-Host Disease.Semantic proximity Read ↗

Refined HLA-DPB1 mismatch with molecular algorithms predicts outcomes in hematopoietic stem cell transplantationSemantic proximity Read ↗

HLA-DPB1 mismatch induces a graft-versus-leukemia effect without severe acute GVHD after single-unit umbilical cord blood transplantation.Semantic proximity Read ↗

The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation.Semantic proximity Read ↗

Clinical outcomes of HLA-DPB1 mismatches in 10/10 HLA-matched unrelated donor-recipient pairs undergoing allogeneic stem cell transplant.Semantic proximity Read ↗

HLA-DPB1 matching in unrelated hematopoietic stem cell transplantation program contributes to a higher incidence of disease relapse.Semantic proximity Read ↗

The Human Leukocyte Antigen-DPB1 Degree of Compatibility Is Determined by Its Expression Level and Mismatch Permissiveness: A German Multicenter Analysis.Semantic proximity Read ↗

Risk associations between HLA-DPB1 T-cell epitope matching and outcome of unrelated hematopoietic cell transplantation are independent of HLA-DPA1Semantic proximity Read ↗

Evolutionary divergence and expression of differential HLA alleles between donor and recipient influence acute GVHD onset after allogenetic HSCTSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.