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Article

Predicting an HLA-DPB1 expression marker based on standard DPB1 genotyping: Linkage analysis of over 32,000 samples.

Human immunology - 1 Jan 2018

Schöne Bianca, Bergmann Sabine, Lang Kathrin, Wagner Ines, Schmidt Alexander H, Petersdorf Effie W, Lange Vinzenz

Abstract excerpt

The risk of acute graft-versus-host disease (GvHD) after hematopoietic stem cell transplantation is increased with donor-recipient HLA-DPB1 allele mismatching. The single-nucleotide polymorphism (SNP) rs9277534 within the 3' untranslated region (UTR) correlates with HLA-DPB1 allotype expression and serves as a marker for permissive HLA-DPB1 mismatches. Since rs9277534 is not routinely typed, we analyzed 32,681...

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Share to 3' Untranslated Regions
Share to Graft vs Host Disease
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Source

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Identifiers

PMID: 29126928
DOI: 10.1016/j.humimm.2017.11.001
PMCID: PMC5743578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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