Article
DPB1 disparities contribute to severe GVHD and reduced patient survival after unrelated donor bone marrow transplantation.
Bone marrow transplantation - 1 Oct 2002
Loiseau P, Espérou H, Busson M, Sghiri R, Tamouza R, Hilarius M, Raffoux C, Devergie A, Ribaud P, Socié G, Gluckman E, Charron D
Abstract excerpt
In order to evaluate the impact of HLA-DBP1 incompatibilities on the occurrence of acute graft-versus-host disease (GVHD) in unrelated hematopoietic cell transplantation, we studied 57 donor/recipient pairs characterized by their allelic identity for HLA-A, B, C, DRB1 and DQB1 and also for DRB3, 4, 5 loci and aimed to correlate DPB1 mismatches to already described risk factors for GVHD using multivariate Cox...
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