Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship of TRIM5 and TRIM22 polymorphisms with liver disease and HCV clearance after antiviral therapy in HIV/HCV coinfected patients.

Journal of translational medicine - 2 Sept 2016

Medrano Luz M, Rallón Norma, Berenguer Juan, Jiménez-Sousa María A, Soriano Vicente, Aldámiz-Echevarria Teresa, Fernández-Rodríguez Amanda, García Marcial, Tejerina Francisco, Martínez Isidoro, Benito José M, Resino Salvador

Abstract excerpt

BACKGROUND AND AIMS: TRIM5 and TRIM22 are restriction factors involved in innate immune response and exhibit anti-viral activity. Single nucleotide polymorphisms (SNPs) at TRIM5 and TRIM22 genes have shown to influence several viral infections such as human immunodeficiency virus (HIV), hepatitis B, as well as measles and rubella vaccination. The aim of this study is to analyze whether TRIM5 and TRIM22...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Chemokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coinfection

Share to Hepacivirus

Share to Hepatitis C, Chronic

Share to Minor Histocompatibility Antigens

Share to Tripartite Motif Proteins

Share to Ubiquitin-Protein Ligases

Source

Open in PubMed Open full text

Identifiers

PMID: 27590274
DOI: 10.1186/s12967-016-1005-7
PMCID: PMC5010694

Genes

TRIM5
TRIM22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship of TRIM5 and TRIM22 polymorphisms with liver disease and HCV clearance after antiviral therapy in HIV/HCV coinfected patients.PMID 27590274Read ↗

Evaluation of TRIM5 and TRIM22 polymorphisms on treatment responses in Iranian patients with chronic hepatitis C virus infection.Semantic proximity Read ↗

A novel TRIM22 gene polymorphism promotes the response to PegIFNα therapy through cytokine-cytokine receptor interaction signaling pathway in chronic hepatitis B.Semantic proximity Read ↗

Toll-like receptor 8 (TLR8) polymorphisms are associated with non-progression of chronic hepatitis C in HIV/HCV coinfected patients.Semantic proximity Read ↗

ADAR1 polymorphisms are related to severity of liver fibrosis in HIV/HCV-coinfected patients.Semantic proximity Read ↗

The role of tripartite motif family members in mediating susceptibility to HIV-1 infectionSemantic proximity Read ↗

Ancient and recent adaptive evolution in the antiviral TRIM22 gene: identification of a single-nucleotide polymorphism that impacts TRIM22 function.Semantic proximity Read ↗

Single nucleotide polymorphisms of CXCL9-11 chemokines are associated with liver fibrosis in HIV/HCV-coinfected patients.Semantic proximity Read ↗

Increased expression and dysregulated association of restriction factors and type I interferon in HIV, HCV mono- and co-infected patients.Semantic proximity Read ↗

Chronic hepatitis C infection and liver disease in HIV-coinfected patients in Asia.Semantic proximity Read ↗

IL28B polymorphisms are associated with severity of liver disease in human immunodeficiency virus (HIV) patients coinfected with hepatitis C virus.Semantic proximity Read ↗

Mx1, OAS1 and OAS2 polymorphisms are associated with the severity of liver disease in HIV/HCV-coinfected patients: A cross-sectional study.Semantic proximity Read ↗

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.