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Article

Evaluation of TRIM5 and TRIM22 polymorphisms on treatment responses in Iranian patients with chronic hepatitis C virus infection.

Gene - 15 Nov 2018

Mobasheri Setareh, Irani Nazanin, Sepahi Abbas Akhavan, Sakhaee Fatemeh, Jamnani Fatemeh Rahimi, Vaziri Farzam, Siadat Seyed Davar, Fateh Abolfazl

Abstract excerpt

The tripartite motif (TRIM)-5 and TRIM22 are involved in innate immune response and show anti-viral activities. The current study aimed at evaluating the association of TRIM5 and TRIM22 polymorphisms with treatment outcomes in patients with chronic hepatitis C virus (CHC). TRIM5 rs3824949 and TRIM22 polymorphisms (rs7113258, rs7935564, and rs1063303) were genotyped using TaqMan polymerase chain reaction (PCR)...

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Topics

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Share to Hepatitis C, Chronic
Share to Interferon-alpha
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Share to Minor Histocompatibility Antigens
Share to Polyethylene Glycols
Share to Sustained Virologic Response
Share to Tripartite Motif Proteins
Share to Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 30017737
DOI: 10.1016/j.gene.2018.07.023

Genes

TRIM22
TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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