Article
Mx1, OAS1 and OAS2 polymorphisms are associated with the severity of liver disease in HIV/HCV-coinfected patients: A cross-sectional study.
Scientific reports - 31 Jan 2017
García-Álvarez Mónica, Berenguer Juan, Jiménez-Sousa María A, Pineda-Tenor Daniel, Aldámiz-Echevarria Teresa, Tejerina Francisco, Diez Cristina, Vázquez-Morón Sonia, Resino Salvador
Abstract excerpt
The mechanisms involved in the chronic hepatitis C progression are incompletely understood. The aim was to analyze the association between 2'5'oligoadenylate synthetase 1,2 and 3 (OAS1-3) and myxovirus resistance proteins 1 (Mx1) polymorphisms and severity of liver disease in human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfected patients. We performed a cross-sectional study in 219 patients that...
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