Article
IL28B polymorphisms are associated with severity of liver disease in human immunodeficiency virus (HIV) patients coinfected with hepatitis C virus.
The Journal of infection - 1 Feb 2013
Guzmán-Fulgencio María, Berenguer Juan, García-Álvarez Mónica, Fernández-Rodríguez Amanda, Jiménez-Sousa María A, Alvarez Emilio, Micheloud Dariela, López Juan Carlos, Miralles Pilar, Cosín Jaime, Catalán Pilar, Resino Salvador
Abstract excerpt
OBJECTIVE: To evaluate the association of IL28B polymorphisms and severity of liver disease among human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfected patients. METHODS: We carried out a cross-sectional study on 223 patients. Liver biopsies were evaluated according to Metavir score. IL28B polymorphisms (rs12980275, rs8099917, rs7248668, and rs11881222) were genotyped using GoldenGate(®) assay....
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