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Article

ADAR1 polymorphisms are related to severity of liver fibrosis in HIV/HCV-coinfected patients.

Scientific reports - 10 Oct 2017

Medrano Luz M, Berenguer Juan, Jiménez-Sousa María A, Aldámiz-Echevarria Teresa, Tejerina Francisco, Diez Cristina, Vigón Lorena, Fernández-Rodríguez Amanda, Resino Salvador

Abstract excerpt

The adenosine deaminase acting on RNA (ADAR1) gene is an interferon-stimulated gene involved in liver injury protection. Our aim was to analyze the association of polymorphisms within this gene with the severity of liver disease in European HIV/HCV-coinfected patients. We performed a cross-sectional study in 220 patients that underwent a liver biopsy. Five SNPs in the ADAR1 gene (rs1127326, rs1127317, rs1127314,...

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Source

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Identifiers

PMID: 29018269
DOI: 10.1038/s41598-017-12885-4
PMCID: PMC5635123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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