Increased expression and dysregulated association of restriction factors and type I interferon in HIV, HCV mono- and co-infected patients.

Abstract excerpt

Host restriction factors and type I interferon are important in limiting HIV and HCV infections, yet the role of HIV, HCV mono- and co-infection in regulating these antiviral genes expression is not clear. In this study, we measured the levels of TRIM5α, TRIM22, APOBEC3G, and IFN-α, -β mRNA expression in peripheral blood mononuclear cells of 43 HIV mono-infected, 70 HCV mono-infected and 64 HIV/HCV co-infected...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to APOBEC-3G Deaminase
• Share to Coinfection