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Article

Genome-wide analysis reveals extensive genetic overlap between childhood phenotypes and later-life type 2 diabetes.

Computers in biology and medicine - 1 Mar 2024

Qiu Shizheng, Sun Yige, Guo Jiahe, Zhang Yu, Hu Yang

Abstract excerpt

Observational studies have indicated a potential influence of childhood phenotypes on the later development of type 2 diabetes (T2D). However, the underlying biological mechanisms remain unclear. In this study, we conducted a comprehensive genome-wide analysis to investigate the shared genetic architecture and genetic loci between nine childhood phenotypes (N = 4202-620,26) and later-life T2D (N = 80,154) using...

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Identifiers

PMID: 38387379
DOI: 10.1016/j.compbiomed.2024.108065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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