Article
Type 2 diabetes-related genetic risk scores associated with variations in fasting plasma glucose and development of impaired glucose homeostasis in the prospective DESIR study.
Diabetologia - 1 Aug 2014
Vaxillaire Martine, Yengo Loïc, Lobbens Stéphane, Rocheleau Ghislain, Eury Elodie, Lantieri Olivier, Marre Michel, Balkau Beverley, Bonnefond Amélie, Froguel Philippe
Abstract excerpt
AIMS/HYPOTHESIS: Genome-wide association studies have firmly established 65 independent European-derived loci associated with type 2 diabetes and 36 loci contributing to variations in fasting plasma glucose (FPG). Using individual data from the Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) prospective study, we evaluated the contribution of three genetic risk scores (GRS) to...
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