Article
Whole-Genome Sequencing and iPLEX MassARRAY Genotyping Map an EMS-Induced Mutation Affecting Cell Competition in Drosophila melanogaster.
G3 (Bethesda, Md.) - 13 Oct 2016
Lee Chang-Hyun, Rimesso Gerard, Reynolds David M, Cai Jinlu, Baker Nicholas E
Abstract excerpt
Cell competition, the conditional loss of viable genotypes only when surrounded by other cells, is a phenomenon observed in certain genetic mosaic conditions. We conducted a chemical mutagenesis and screen to recover new mutations that affect cell competition between wild-type and RpS3 heterozygous cells. Mutations were identified by whole-genome sequencing, making use of software tools that greatly facilitate...
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