Article

Cost-effective mapping of genetic interactions in mammalian cells

2021-04-29

Abstract excerpt

Comprehensive maps of genetic interactions in mammalian cells are daunting to construct because of the large number of potential interactions, ~ 2 × 10 8 for protein coding genes. We previously used co-inheritance of distant genes from published radiation hybrid (RH) datasets to identify genetic interactions. However, it was necessary to combine six legacy datasets from four species to obtain adequate statistical...

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Literature Corpus work: 0fb0735b-d905-5fec-80db-7f5018f35978
DOI: 10.1101/2021.04.29.441342

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