Article
Characterization of the DNA-Mediated Oxidation of Dps, A Bacterial Ferritin.
Journal of the American Chemical Society - 7 Sept 2016
Arnold Anna R, Zhou Andy, Barton Jacqueline K
Abstract excerpt
Dps proteins are bacterial ferritins that protect DNA from oxidative stress and have been implicated in bacterial survival and virulence. In addition to direct oxidation of the Dps iron sites by diffusing oxidants, oxidation from a distance via DNA charge transport (CT), where electrons and electron holes are rapidly transported through the base-pair π-stack, could represent an efficient DNA protection mechanism...
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