Article
Dynamics and mechanisms of DNA repair by photolyase.
Physical chemistry chemical physics : PCCP - 14 May 2015
Liu Zheyun, Wang Lijuan, Zhong Dongping
Abstract excerpt
Photolyases, a class of flavoproteins, use blue light to repair two types of ultraviolet-induced DNA damage, a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4) photoproduct (6-4PP). In this perspective, we review the recent progress in the repair dynamics and mechanisms of both types of DNA restoration by photolyases. We first report the spectroscopic characterization of flavin in various...
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