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Article

UvrC Coordinates an O2-Sensitive [4Fe4S] Cofactor.

Journal of the American Chemical Society - 24 Jun 2020

Silva Rebekah M B, Grodick Michael A, Barton Jacqueline K

Abstract excerpt

Recent advances have led to numerous landmark discoveries of [4Fe4S] clusters coordinated by essential enzymes in repair, replication, and transcription across all domains of life. The cofactor has notably been challenging to observe for many nucleic acid processing enzymes due to several factors, including a weak bioinformatic signature of the coordinating cysteines and lability of the metal cofactor. To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32470300
DOI: 10.1021/jacs.0c01671
PMCID: PMC7392197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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