Protection of DNA during oxidative stress by the nonspecific DNA-binding protein Dps.

doi:10.1128/jb.179.16.5188-5194.1997

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Article

Protection of DNA during oxidative stress by the nonspecific DNA-binding protein Dps.

Journal of bacteriology - 1 Aug 1997

Martinez A, Kolter R

Abstract excerpt

Reactive oxygen species can damage most cellular components, but DNA appears to be the most sensitive target of these agents. Here we present the first evidence of DNA protection against the toxic and mutagenic effects of oxidative damage in metabolically active cells: direct protection of DNA by...

Topics

Bacterial Proteins
DNA Damage
DNA Repair
DNA, Bacterial
DNA-Binding Proteins
Escherichia coli
Hydrogen Peroxide
Mutagenesis
Mutation
Oxidative Stress

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