Article
Helicobacter hepaticus Dps protein plays an important role in protecting DNA from oxidative damage.
Free radical research - 1 Jun 2006
Hong Yang, Wang Ge, Maier Robert J
Abstract excerpt
The ferritin-like DNA-binding protein from starved cells (Dps) family proteins are present in a number of pathogenic bacteria. Dps in the enterohepatic pathogen, Helicobacter hepaticus is characterized and a H. hepaticus dps mutant was generated by insertional mutagenesis. While the wild type H. hepaticus cells were able to survive in an atmosphere containing up to 6.0% O2, the dps mutant failed to grow in 3.0%...
Topics
- Bacterial Proteins
- Cell Shape
- DNA
- DNA Damage
- DNA-Binding Proteins
- Gene Expression Regulation, Bacterial
- Guanine
- Helicobacter hepaticus
- Iron
- Mutation
- Oxidation-Reduction
- Oxygen
- Protein Binding