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Article

MDM2 344T>A polymorphism; could it be a predictive marker of anthracycline resistance?

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Arfaoui Abir, Douik Hayet, Kablouti Ghalia, Chaaben Arijben, Handiri Nadia, Zid Zaineb, Ouni Nesrine, Zouiouch Farah, Ayari Fayza, Mamoghli Tensime, Bouassida Jihen, Harzallah Latifa, Guemira Fethi

Abstract excerpt

PURPOSE: To find a possible association between the Mouse Double Minute 2(MDM2) 344T>A, alone and in combination with p53 72 Arg/Pro polymorphism, and resistance to anthracycline-based chemotherapy of breast cancer in Tunisia. METHODS: This study enrolled 542 patients with invasive ductal carcinoma (IDC) treated with anthracycline-based chemotherapy. Genomic DNA was isolated from whole blood, using the phenol...

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PMID: 27569097

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MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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