[Association of murine double minute 2 and P53 polymorphisms with breast cancer susceptibility].

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[Association of murine double minute 2 and P53 polymorphisms with breast cancer susceptibility].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Feb 2013

Wang Mei-li, Xu Yun-xia, Qian Jian, Wang Fen-hua

Abstract excerpt

OBJECTIVE: To investigate the combined effects between the two polymorphisms murine double minute 2 (MDM2) rs2279744 T→G and P53 rs1042522 G→C on the genetic susceptibility of breast cancer. METHODS: A total of 600 female patients with diagnosed breast cancer were consecutively recruited from the Yuhang district, Hangzhou city during March 2001 to May 2009. In the same period as the cases were collected, 600...

Topics

Adult
Breast Neoplasms
Case-Control Studies
Female
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Middle Aged

Polymorphism, Single Nucleotide

Proto-Oncogene Proteins c-mdm2

Risk Factors

Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 23719102

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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