Article
Role of p53 Codon72 SNP in breast cancer risk and anthracycline resistance.
Anticancer research - 1 Mar 2015
Arfaoui Abir, Douik Hayet, Kablouti Ghalia, Chaaben Arij Ben, Handiri Nedia, Zid Zeineb, Ouni Nessrine, Zouiouch Farah, Ayari Faiza, Mamoughli Tesnim, Bouassida Jihen, Abazza Hajer, Harzallaha Latif, Guemira Fethi
Abstract excerpt
BACKGROUND/AIM: We undertook a case-control and a case-case study to examine the possible association of p53 codon72 polymorphism with the breast cancer risk and resistance to anthracycline-based chemotherapy. PATIENTS AND METHODS: Case-control study: This study enrolled 175 patients with breast cancer treated at the Salah Aziez Institute and 159 healthy Tunisian women (matched for age, ethnicity and origin),...
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