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Article

Analysis of the Association between MDM4 rs4245739 Single Nucleotide Polymorphism and Breast Cancer Susceptibility.

Clinical laboratory - 1 Jul 2016

Pedram Negar, Pouladi Nasser, Feizi Mohammad A Hosseinpour, Montazeri Vahid, Sakhinia Ebrahim, Estiar Mehrdad A

Abstract excerpt

BACKGROUND: MDM4 is a negative regulator of the p53 tumor suppression pathway. Recent studies have revealed that the rs4245739 A>C polymorphism of MDM4 in the 3-untranslated region makes it a miR-191 target site which leads to lower MDM4 expression. This study is aimed to detect if rs4245739 single nucleotide polymorphism (SNP) of the MDM4 gene influences the breast cancer development in Iranian-Azeri women....

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Source

Identifiers

PMID: 28164646
DOI: 10.7754/Clin.Lab.2016.151128

Genes

MDM4

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Analysis of the Association between MDM4 rs4245739 Single Nucleotide Polymorphism and Breast Cancer Susceptibility.PMID 28164646Read ↗

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Associations of MDM2 and MDM4 Polymorphisms with Early-Stage Breast CancerSemantic proximity Read ↗

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