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Article

GRK5-Knockout Mice Generated by TALEN-Mediated Gene Targeting.

Animal biotechnology - 1 Oct 2016

Nanjidsuren Tsevelmaa, Park Chae-Won, Sim Bo-Woong, Kim Sun-Uk, Chang Kyu-Tae, Kang Myung-Hwa, Min Kwan-Sik

Abstract excerpt

Transcription activator-like effector nucleases (TALENs) are a new type of engineered nuclease that is very effective for directed gene disruption in any genome sequence. We investigated the generation of mice with genetic knockout (KO) of the G protein-coupled receptor kinase (GRK) 5 gene by microinjection of TALEN mRNA. TALEN vectors were designed to target exons 1, 3, and 5 of the mouse GRK5 gene. Flow...

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Source

Identifiers

PMID: 27565865
DOI: 10.1080/10495398.2016.1176032

Genes

GRK5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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