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Article

Regulation of Polycystin-1 Function by Calmodulin Binding.

PloS one - 1 Jan 2016

Doerr Nicholas, Wang Yidi, Kipp Kevin R, Liu Guangyi, Benza Jesse J, Pletnev Vladimir, Pavlov Tengis S, Staruschenko Alexander, Mohieldin Ashraf M, Takahashi Maki, Nauli Surya M, Weimbs Thomas

Abstract excerpt

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disease that leads to progressive renal cyst growth and loss of renal function, and is caused by mutations in the genes encoding polycystin-1 (PC1) and polycystin-2 (PC2), respectively. The PC1/PC2 complex localizes to primary cilia and can act as a flow-dependent calcium channel in addition to numerous other signaling functions. The exact...

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PMID: 27560828
DOI: 10.1371/journal.pone.0161525
PMCID: PMC4999191

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STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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