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Article

Gating of the polycystin ion channel signaling complex in neurons and kidney cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2004

Delmas Patrick, Nauli Surya M, Li Xiaogang, Coste Bertrand, Osorio Nancy, Crest Marcel, Brown David A, Zhou Jing

Abstract excerpt

Mutations in either polycystin-2 (PC2) or polycystin-1 (PC1) proteins cause severe, potentially lethal, kidney disorders and multiple extrarenal (including brain) disease phenotypes. PC2, a member of the transient receptor potential channel superfamily, and PC1, an orphan membrane receptor of lar...

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Source

Identifiers

PMID: 14766803
DOI: 10.1096/fj.03-0319fje

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14766803-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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