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Article

PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain.

Neuroscience - 29 Oct 2016

Hegde Shweta, Ji Hao, Oliver David, Patel Neema S, Poupore Nicolas, Shtutman Michael, Kelly Michy P

Abstract excerpt

Despite the fact that appropriate social behaviors are vital to thriving in one's environment, little is understood of the molecular mechanisms controlling social behaviors or how social experience sculpts these signaling pathways. Here, we determine if Phosphodiesterase 11A (PDE11A), an enzyme that is enriched in the ventral hippocampal formation (VHIPP) and that breaks down cAMP and cGMP, regulates social...

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Identifiers

PMID: 27544407
DOI: 10.1016/j.neuroscience.2016.08.019
PMCID: PMC5031549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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