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Article

[Analysis of Heteroplasmy in the Major Noncoding Region of Mitochondrial DNA in the Blood and Atherosclerotic Plaques of Carotid Arteries].

Genetika - 1 Apr 2016

Golubenko M V, Nazarenko M S, Frolov A V, Sleptsov A A, Markov A V, Glushkova M E, Barbarash O L, Puzyrev V P

Abstract excerpt

For identification of somatic mitochondrial DNA (mtDNA) mutations, the mtDNA major noncoding region (D-loop) sequence in blood samples and carotid atherosclerosis plaques from patients with atherosclerosis was analyzed. Five point heteroplasmic positions were observed in 4 of 23 individuals (17%). Only in two cases could heteroplasmy have resulted from somatic mutation, whereas three heteroplasmic positions were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27529986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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