Article
Association of mutations in the mitochondrial genome with the subclinical carotid atherosclerosis in women.
Experimental and molecular pathology - 1 Aug 2015
Sazonova Margarita A, Chicheva Mariya M, Zhelankin Andrey V, Sobenin Igor A, Bobryshev Yuri V, Orekhov Alexander N
Abstract excerpt
The importance of the study of an association of mitochondrial DNA mutations with asymptomatic atherosclerosis in women is undeniable. In the present study, a series of PCR with primers for mutation region and further amplificate pyrosequencing were carried out to identify point substitutions or microdeletions of the mitochondrial genome. The results obtained were processed using the original method of estimating...
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