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Article

Mutation C3256T of mitochondrial genome in white blood cells: novel genetic marker of atherosclerosis and coronary heart disease.

PloS one - 1 Jan 2012

Sobenin Igor A, Sazonova Margarita A, Ivanova Maria M, Zhelankin Andrey V, Myasoedova Veronika A, Postnov Anton Y, Nurbaev Serik D, Bobryshev Yuri V, Orekhov Alexander N

Abstract excerpt

This study was undertaken to examine the association between the level of heteroplasmy for the mutation C3256T in human white blood cells and the extent of carotid atherosclerosis, as well as the presence of coronary heart disease (CHD), the major clinical manifestation of atherosclerosis. Totally, 191 participants (84 men, 107 women) aged 65.0 years (SD 9.4) were recruited in the study; 45 (24%) of them had CHD....

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Identifiers

PMID: 23056349
DOI: 10.1371/journal.pone.0046573
PMCID: PMC3462756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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