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Article

Mosaicism of mitochondrial genetic variation in atherosclerotic lesions of the human aorta.

BioMed research international - 1 Jan 2015

Sazonova Margarita A, Sinyov Vasily V, Barinova Valeria A, Ryzhkova Anastasia I, Zhelankin Andrey V, Postnov Anton Y, Sobenin Igor A, Bobryshev Yuri V, Orekhov Alexander N

Abstract excerpt

OBJECTIVE: The aim of the present study was an analysis of heteroplasmy level in mitochondrial mutations 652delG, A1555G, C3256T, T3336C, 652insG, C5178A, G12315A, G13513A, G14459A, G14846A, and G15059A in normal and affected by atherosclerosis segments of morphologically mapped aortic walls. METHODS: We investigated the 265 normal and atherosclerotic tissue sections of 5 human aortas. Intima of every aorta was...

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Identifiers

PMID: 25834827
DOI: 10.1155/2015/825468
PMCID: PMC4365331

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Source receipt: pubmed, retrieved 7 Sept 2026.

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