Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial mutations are associated with atherosclerotic lesions in the human aorta.

Clinical & developmental immunology - 1 Jan 2012

Sobenin Igor A, Sazonova Margarita A, Postnov Anton Y, Bobryshev Yuri V, Orekhov Alexander N

Abstract excerpt

Somatic mutations of the human mitochondrial genome can be a possible determinant of atherosclerosis. To test this possibility, forty mitochondrial mutations were analyzed in the present study in order to see which of these mutations might be associated with atherosclerosis. Ten mitochondrial mutations belonging to mitochondrial genes MT-RNR1 (rRNA 12S); MT-TL1 (tRNA-Leu, recognizes UUR); MT-TL2 (tRNA-Leu,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Diseases
Share to Cytochromes b
Share to Electron Transport Complex I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Mitochondrial

Share to NADH Dehydrogenase

Share to Orphan Nuclear Receptors

Share to Plaque, Atherosclerotic

Share to Receptors, Tumor Necrosis Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 22997526
DOI: 10.1155/2012/832464
PMCID: PMC3446814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial mutations are associated with atherosclerotic lesions in the human aorta.PMID 22997526Read ↗

Changes of mitochondria in atherosclerosis: possible determinant in the pathogenesis of the disease.Semantic proximity Read ↗

[Association of mitochondrial genome mutations with lipofibrous plaques in human aortic intima].Semantic proximity Read ↗

Mutations of mitochondrial DNA in atherosclerosis and atherosclerosis-related diseases.Semantic proximity Read ↗

Mosaicism of mitochondrial genetic variation in atherosclerotic lesions of the human aorta.Semantic proximity Read ↗

Role of Mitochondrial Genome Mutations in Pathogenesis of Carotid Atherosclerosis.Semantic proximity Read ↗

Mitochondrial mutations in atherosclerosis: new solutions in research and possible clinical applications.Semantic proximity Read ↗

Association of mitochondrial genetic variation with carotid atherosclerosis.Semantic proximity Read ↗

Association of mutations in the mitochondrial genome with the subclinical carotid atherosclerosis in women.Semantic proximity Read ↗

Studies of the human aortic intima by a direct quantitative assay of mutant alleles in the mitochondrial genome.Semantic proximity Read ↗

Mitochondrion as a Selective Target for the Treatment of Atherosclerosis: Role of Mitochondrial DNA Mutations and Defective Mitophagy in the Pathogenesis of Atherosclerosis and Chronic Inflammation.Semantic proximity Read ↗

Genetics of Arterial-Wall-Specific Mechanisms in Atherosclerosis: Focus on Mitochondrial Mutations.Semantic proximity Read ↗

[Analysis of Heteroplasmy in the Major Noncoding Region of Mitochondrial DNA in the Blood and Atherosclerotic Plaques of Carotid Arteries].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.