Article
Association of mitochondrial genetic variation with carotid atherosclerosis.
PloS one - 1 Jan 2013
Sobenin Igor A, Sazonova Margarita A, Postnov Anton Y, Salonen Jukka T, Bobryshev Yuri V, Orekhov Alexander N
Abstract excerpt
In human pathology, several diseases are associated with somatic mutations in the mitochondrial genome (mtDNA). Even though mitochondrial dysfunction leads to increased oxidative stress, the role of mitochondrial mutations in atherosclerosis has not received much attention so far. In this study w...
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