Article
Role of Mitochondrial Genome Mutations in Pathogenesis of Carotid Atherosclerosis.
Oxidative medicine and cellular longevity - 1 Jan 2017
Sazonova Margarita A, Sinyov Vasily V, Ryzhkova Anastasia I, Galitsyna Elena V, Khasanova Zukhra B, Postnov Anton Yu, Yarygina Elena I, Orekhov Alexander N, Sobenin Igor A
Abstract excerpt
Mutations of mtDNA, due to their higher frequency of occurrence compared to nuclear DNA mutations, are the most promising biomarkers for assessing predisposition of the occurrence and development of atherogenesis. The aim of the present article was an analysis of correlation of several mitochondrial genome mutations with carotid atherosclerosis. Leukocytes from blood of study participants from Moscow polyclinics...
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